Healthcare · Medical Physics & Cancer Research

The physics of imaging became the physics of treatment.

Capacitive fields that map permittivity inside the brain and breast — and, applied at different parameters, selectively disrupt cancer cell division from outside the body. Wearable. No radiation. Over 5,000 patients.

5,000+
Patients reached through ECCT
<300 kHz
ECCT therapeutic frequency range
<30 Vpp
Field intensity — no ionising radiation
2012
ECCT patent granted
The biological medium

Biological tissue satisfies the same physical condition as an industrial vessel: it is dielectric.

The ECVT framework rests on a physical fact: the medium being imaged holds and transmits capacitive fields in patterns that encode its internal structure. Biological tissue satisfies the same condition. The capacitance measurements taken at the boundary of a pressurised process vessel translate directly to measurements at the boundary of a body.

Real-time volumetric (4D) imaging of human brain activity using ECVT was first proposed — a helmet-shaped 32-channel sensor array, data acquisition system, and computer system for reconstruction and display of brain activity on the scalp and inside the brain. The ECVT system comprises the helmet-shaped capacitive sensor, 32-channel DAS, and PC for real-time reconstruction. In 2013, Warsito and Baidillah demonstrated brain tumour detection using ECVT at the IEEE EMBS Conference on Neural Engineering (November 2013) — localising charge accumulation in tumour tissue in both hemispheres and producing 3D volumetric reconstructions of cerebellar structures. A healthy brain shows high, homogeneous cortical activity; abnormalities — tumours, epileptic foci, pressure changes — appear as localised low-activity regions. Validation of ECVT permittivity maps against MRI and biopsy confirmed that malignant and benign tissue are distinguishable through dielectric contrast alone.

Prolonged study of capacitive field interactions with living cells yielded a finding beyond imaging. At frequencies below 300 kHz, these fields interfere selectively with the mitotic spindle in rapidly dividing cells. The physical selectivity mechanism: the electrically charged protein structures that form the spindle during mitosis interact with the applied field in ways determined by the cell's membrane potential and division rate. Cancer cells — dividing faster, with altered membrane potentials — are preferentially disrupted. Normal tissue, dividing far more slowly, is largely unaffected. Warsito patented ECCT in 2012.

From field to disruption

How a capacitive field outside the body reaches cancer cells within it.

01
Helmet or conforming sensor
32-channel electrode array at body surface. For imaging: helmet-shaped for brain, conforming for breast. For ECCT therapy: body-conforming garment placed over tumour site. No surgery, no injection, no hospital admission.
02
Sub-300 kHz field
Low-frequency capacitive field propagates through tissue without ionising radiation. Maximum intensity below 30 Vpp. ECVT imaging uses the same frequency range to map permittivity — therapy redirects the same physics toward cellular disruption.
03
Mitotic spindle interaction
Field interacts with electrically charged protein structures during cell division (Abdulhakim Coskun, Biophysicist, Georgia Institute of Technology). Cancer cells — dividing rapidly with altered membrane potentials — are preferentially affected. The selectivity is physical, not chemical.
04
Selective disruption
Mitotic arrest and apoptosis in rapidly dividing cancer cells. In vitro: reduced proliferation in MCF-7 breast cancer cell lines. In vivo: inhibited tumour growth in murine models with cytokine changes indicating immune microenvironment modulation.
05
4D imaging monitors progress
Real-time brain ECVT — cortical and intracranial activity reconstructed volumetrically — allows clinicians to monitor lesion response as therapy proceeds. Radiation-free, continuous, at bedside.
What the studies confirmed

From laboratory cell lines to clinical populations.

The biological chain from capacitive field to cancer cell death has been validated at every level. Coskun's biophysics work established the physical mechanism — spindle protein interaction under sub-300 kHz fields — in cellular models. MCF-7 breast cancer cell line studies confirmed reduced proliferation in vitro. Murine in vivo studies showed inhibited tumour growth alongside changes in cytokine expression suggesting modulation of the tumour immune microenvironment.

Baidillah and Warsito's brain ECVT work (IEEE EMBS 2013) demonstrated that the same 32-channel sensor that maps brain activity can detect tumour charge accumulation volumetrically — providing a radiation-free imaging platform that works alongside ECCT therapy. The Japan-based clinical programme and oncology research partnerships extended the findings to over 5,000 patients across glioblastoma, breast, liver, and cervical cancers. Ahmad Novian's dosimetry work established field intensity measurement and frequency optimisation per cancer type.

  • MCF-7 breast cancer: reduced proliferation in vitro under sub-300 kHz fields
  • Murine models: inhibited tumour growth; cytokine changes indicating immune modulation
  • Brain ECVT: tumour localisation in both hemispheres + 3D cerebellar reconstruction (Baidillah & Warsito, IEEE EMBS 2013)
  • Brain activity imaging: executed movement vs imagined movement resolved in real-time 4D (Baidillah et al.)
  • Keserci: ECVT permittivity contrast validated against MRI, PET-CT, and biopsy
  • 5,000+ patients: glioblastoma, breast, liver, cervical — Akayama (Japan), Kaplan (oncology)
Clinical scope

Where the research has been applied.

From laboratory cell studies to wearable therapy across thousands of patients.

Brain ECVT Imaging

32-channel helmet sensor maps permittivity distribution within the brain volume in real time — cortical activity, intracranial activity, tumour localisation, and 3D cerebellar reconstruction. No radiation, no contrast agents.

Breast ECVT Imaging

Volumetric permittivity maps distinguishing malignant, benign, cyst, and normal tissue through dielectric contrast — confirmed against biopsy findings by Keserci. Correlates with PET-CT FDG uptake without radiation dose.

Glioblastoma

ECCT delivered via helmet garment. Warsito's initial clinical programme: stage-4 cases including complete remission. Akayama's Japan programme extended to broader patient cohorts.

Breast Cancer

MCF-7 proliferation reduction confirmed in vitro. Wearable garment format for home delivery. Murine in vivo results established the immune modulation context for clinical application.

Liver & Cervical Cancers

Conforming electrode garments adapted to each anatomical site. Kaplan's oncology research and Akayama's clinical programme cover these cancer types alongside glioblastoma and breast.

Neuroscience Research

ECVT brain research — executed movement, imagined movement, cortical mapping — extends the healthcare imaging platform into functional brain research and brain-computer interface applications.

Products

ECCT & ECVT Healthcare System

ECCT delivers sub-300 kHz capacitive therapy through body-conforming wearable garments — for home use, without radiation or systemic toxicity. The ECVT Healthcare System provides radiation-free 4D imaging for brain and breast clinical applications. Both built on the same 32-channel capacitive measurement core established in the published research.

Selected publications

01
Warsito W., Baidillah M.R.
Brain Tumor Detection Using Electrical Capacitance Volume Tomography (ECVT)
IEEE EMBS Conference on Neural Engineering, November 2013
02
Baidillah M.R., Sulaiman R.I., Aljohani M.S.
Electrical Capacitance Volume Tomography for Human Brain Motion Activity Observation
Real-time 4D brain activity imaging — first proposal
03
Warsito W.P. (inventor)
Electro-Capacitive Cancer Therapy (ECCT)
Patent granted 2012 — frequency <300 kHz, intensity <30 Vpp, capacitive electrode garment delivery
04
Baidillah M.R., Mukhlisin M., Taruno W.P.
Comparison of Sensor Geometries for ECVT
Int'l Journal of Innovative Computing, Information and Control, 2013, vol. 9, no. 11